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Hope is on the Horizon

Clinical Trial Participation


If you have been diagnosed with Lupus or another medical condition and you are frustrated with the lack of safe and effective treatment choices currently available, then you may want to consider participating in a clinical research trial. Please keep in mind that making the choice to participate in a clinical study is a very personal decision that should be based on discussions between you, your loved ones, and your treating healthcare providers that are the most familiar with your medical history.  We cannot emphasize this point strongly enough.  


Clinical Trial Search Tool 


We are very excited to partner with Antidote to launch a clinical research trial search tool. To begin searching for trials for Lupus or another disease, click on the white Start button and respond to the prompts. You will then be asked to answer several questions to help narrow down and identify possible clinical trials for you.  

Purple microscope, match to clinical trials in 60 seconds

Clinical Trial Resources


Clinical Trials - a service of the US NIH is a database of privately and publicly funded clinical studies conducted around the world.


The Center for Information & Study on Clinical Research Participation (CISCRP)
CISCRP (Center for Information and Study on Clinical Research Participation) is a first-of-its-kind nonprofit organization dedicated to educating and informing the public, patients, medical/research communities, the media, and policy makers about clinical research and the role each party plays in the process.
Learn more at


Coalition for Clinical Trials Awareness (CCTA)
The mission of the Coalition for Clinical Trials Awareness is to advocate for the creation of a federally sponsored public awareness campaign to increase the public’s understanding of the benefits of clinical trials. 
Learn more at


United States National Library of Medicine, National Institutes of Health 
The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, has been a center of information innovation since its founding in 1836. The world’s largest biomedical library, NLM maintains and makes available a vast print collection and produces electronic information resources on a wide range of topics that are searched billions of times each year by millions of people around the globe. It also supports and conducts research, development, and training in biomedical informatics and health information technology. In addition, the Library coordinates a 6,500-member Network of the NLM that promotes and provides access to health information in communities across the United States. 
Learn more at


Office of Research on Women's Health, Office of the NIH Director, National Institutes of Health/DHHS
ORWH is the first Public Health Service office dedicated specifically to promote women's health research within and beyond the NIH scientific community. Women's health research is an essential part of the NIH research agenda. The field includes the study of health throughout the lifespan and across the spectrum of scientific investigations. Learn more at



Current Lupus Studies


DxTerity Diagnostics, a Los Angeles based genomics company, is sponsoring an observational research study that uses participant’s health information and a few drops of blood to better understand what it means to live with and manage lupus. They are looking to find a better, easier, and more convenient way for people living with lupus to track and manage their disease from home.
Learn more at


Amgen is conducting a global phase 2b study to evaluate the safety and efficacy of an investigational drug in people with systemic lupus erythematosus (SLE) who have continued disease activity despite current therapy. Participants enrolled in the VIOLET study are expected to attend study visits for ~1 year. The trial is being conducted in approximately 20 countries and is available to those who are not responding to the current standard of care and meet the eligibility criteria.
Learn more at TheVioletStudy


Kezar Life Sciences is evaluating an investigational medication in a clinical research study to determine whether it can help people living with lupus nephritis (LN). They are currently looking for participants with lupus nephritis to be enrolled into the Phase 2 portion of the study at multiple clinical trial sites in the United States.
Learn more at 


Janssen is sponsoring a global phase 2 study evaluating the safety and effectiveness of an investigational medication in people with systemic lupus erythematosus (SLE). The study is seeking participants aged 18-65       diagnosed with systemic lupus erythematosus (SLE) 6 months ago or more.
Learn more at

CARE Study

Idorsia Pharmaceuticals is evaluating an investigational medication in a global phase 2 clinical research study for treating patients with lupus. The main aim of the study is to see whether this drug reduces the symptoms of lupus. In addition, the patient’s quality of life and fatigue will also be assessed to fully understand the impact of the investigational treatment. 
Learn more at


Biogen's TOPAZ Study is evaluating the safety and potential efficacy of an investigational medication in people with active systemic lupus erythematosus (SLE) who are still taking their current SLE non-biologic therapy. The TOPAZ Studies will last for a year and a half and include approximately 22 visits to the study site and are being conducted in over 25 countries. 
Learn more at

20170588 SLE Study
Amgen is conducting a clinical trial to determine if an investigational drug with an innovative mechanism of action, targeting both the T cells and B cells activity simultaneously, could be a safe and effective treatment for people with systemic lupus erythematosus (SLE) with ongoing disease activity despite treatment with standard of care therapies. This is a dose ranging, adaptive design phase 2b global study currently being conducted in approximately 19 countries. Participants are expected to attend study visits for ~1 year and follow-up visits for 16 weeks after last dose of investigational drug. 
Learn more at 20170588 SLE Study

UCB, a global biopharmaceutical company, in collaboration with Biogen, is evaluating an investigational drug in a global phase 3 clinical research study for treating patients with lupus. The purpose of the study is to evaluate the potential ability of the investigational drug as an add-on treatment to standard of care (SOC) medication to achieve clinically relevant long-term improvement of moderate to severe disease activity.
Learn more at Lupus (

Equillium, Inc. is evaluating an investigational medicine in a phase 1b clinical research study in patients with Systemic Lupus Erythematosus (SLE). They are looking for participants with active proliferative lupus nephritis to be enrolled in the second portion of the study at multiple clinical trial sites in the United States and India.
Learn more at


          Current List of Lupus Research Trials in Boston, MA area.


          Current list of Lupus Research Trials in Chicago, IL area.



Learn About Clinical Trial Opportunities 

To learn about lupus clinical research trial opportunities go to

  1. Type lupus in the search box and click on the search button. 

  2. Then click on the On Map tab at the top. 

  3. Click on the Geographic Area, Country or State you are interested in and the studies for that area will be listed.

  4. Click on a specific study for details about the trial's purpose, study eligibility, inclusion and exclusion criteria, locations, and contact information. 

The Lupus and Allied Diseases Association, Inc., would like to thank Kathleen Arntsen for her efforts in developing the Hope is on the Horizon program and resource material originally developed in 2004 and copyrighted in 2007.

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